Moronic best friends get themselves locked inside the Bio-Dome, a science experiment, along with a group of environmental scientists for one year.
as Bud Macintosh
as Doyle Johnson
as Dr. Noah Faulkner
as Monique
as Jen
as William Leaky
as T.C. Romulus
as Olivia Biggs
as Mimi Simkins
as Denise
as Russell
as Doyle's Mother
as Trent
as Parker
as Roach
as Dr. Petra von Kant
as Tenacious D
as Tenacious D
as Partier
as Drummer
as Young Doyle
as Young Bud
as Guard
as Reporter Joachim West
as Prof. Bloom
as Guy
as Singer
as Guitarist
as Partier
as Bio-Dome Technician
as Anchor Aries West
as Vigilante
as Vigilante
as Cmdr. Gates, SWAT Team
as Assistant
as Assistant
as Narrator
as Axl
as Woman in Bandstand
