
A horrific explosion creates a dimensional portal between Tromaville and its dimensional mirror image, Amortville. While the Toxie is trapped in the mirror dimension, Tromaville comes under the control of his evil doppelganger, the Noxious Offender.

as Toxic Avenger / Noxious Offender

as Ms. Weiner

as Toxie (voice)

as Sarah / Claire

as Mayor Goldberg

as Painter

as Sgt. Kabukiman / Evil Kabukiman

as Prologue / Epilogue Narrator (voice)

as Chester / Lardass

as Sgt. Kazinski

as Tito

as Sweetie Honey

as Pompey

as Sarah's Gynecologist

as Tex Diaper

as Evil Melvin

as Amortville Police Chief

as Lucifer

as Abortion Counselor

as Dr. Flem Hocking

as Press Secretary

as Award Presenter

as Rex Diaper

as Man Hit by Car

as Dr. Hocking's Nurse

as Wet Lesbian

as Good Lemmy / Bad Lemmy

as Herself (Facelift Death)

as Himself (Breast Smoosh Death)

as Beautiful Interpretative Dancer

as Beautiful Young Boy

as President of the United States

as Tromaville / Amortville Citizen

as Man in Public Service Announcement

as Glamorous Gyno-American

as Glamorous Gyno-American

as Glamorous Gyno-American

as Glamorous Gyno-American

as Glamorous Gyno-American

as Glamorous Gyno-American

as God

as Glamorous Gyno-American / Naked Nurse (as Celeste Octavian)

as Lesbian Art Student

as Wet Lesbian / Topless Deaf Translator

as Diaper Mafia Temptress

as Glamorous Gyno-American

as Randy Diaz

as Jason Gonzalez

as Nurse

as Tromaville Nazi #2

as Tromaville Nazi - Angry Tromaville Citizen- Amortvillain